SLU-PP-332 5mg | ERR agonist | Estrogen Related Receptor Agonist

SLU-PP-332 5mg – ERR (Estrogen-Related Receptor) Agonist Research Compound

 

 

SLU-PP-332 is a synthetic small-molecule research compound widely referenced in preclinical literature for its activity as an estrogen-related receptor (ERR) agonist. It is used in controlled laboratory research focused on nuclear receptor signalling, cellular metabolism, mitochondrial function, and oxidative bioenergetics, particularly in experimental models investigating metabolic regulation pathways.

 

ERRs (Estrogen-Related Receptors) are a subset of nuclear receptors that are studied for their involvement in transcriptional control of genes associated with mitochondrial biogenesis, energy utilisation, and oxidative phosphorylation pathways. SLU-PP-332 serves as a tool compound for characterising ERR-mediated mechanisms in vitro and in preclinical systems, distinct from classical estrogen receptor modulation.

 

 

 

 

⚙️ Peptide/Compound Specifications

 

 

• Compound Name: SLU-PP-332
• Class: Small-molecule ERR agonist research compound
• CAS / Identifier: Referenced in peer-reviewed sources as ERR pathway probe compound
• Molecular Formula: C₁₆H₁₀F₃N₃O₃ (typical published structure for SLU-PP-332 scaffold)
• Molecular Weight: ~345.26 g/mol (based on published ERR agonist scaffold data)
• IUPAC Reference: consistent with experimental ERR agonist class structures
• Appearance: Off-white to pale powder
• Form: Lyophilised / dry research compound
• Purity: ≥99% (HPLC verified)
• Solubility: Soluble in DMSO or appropriate laboratory solvents such as a relevant Bacteriostatic Water (lab use only)
• Storage: 2–8 °C (short term) / –20 °C (long term, protected from light)

 

 

 

 

 

🔬 Scientific Insight & Research Context

 

 

 

Estrogen-Related Receptor (ERR) Agonist Activity

 

 

• SLU-PP-332 is characterised in preclinical research as an ERRα (NR3B1) agonist, used to investigate ERR-activated transcriptional networks in controlled cellular systems.
• ERRs are orphan nuclear receptors closely related to estrogen receptors but function independently of estrogen ligands. ERR agonists like SLU-PP-332 are tools for probing ERR-mediated gene expression in metabolic regulation studies.

 

 

 

Metabolic and Mitochondrial Regulation

 

 

• ERR agonists are commonly used in research on mitochondrial biogenesis, oxidative phosphorylation, lipid oxidation, and fuel utilisation pathways, particularly in metabolic systems with high energy demand signalling.
• SLU-PP-332’s role in these models helps researchers characterise nuclear receptor–mediated transcriptional control of key metabolic enzymes and mitochondrial regulators.

 

 

 

• ERR agonist compound
• Estrogen-related receptor research probe
• Nuclear receptor signalling research
• Mitochondrial regulatory pathways
• Metabolic transcriptional control
• Oxidative bioenergetics research tool

 

 

 

 

 

📦 Product Details

 

 

• Quantity: 5mg per vial
• Grade: Research use reagent (RUO)
• Intended Use: Laboratory and preclinical research models

 

 

 

 

 

🧪 Storage & Handling

 

 

Store in a cool, dry environment, protected from light and moisture.

For extended preservation, refrigeration or freezing is recommended.

Use in accordance with standard laboratory protocols for research compounds.

 

 

 

 

⚠️ Research Use Only

 

 

This product is supplied for laboratory research purposes only.

Not intended for human, clinical, or veterinary use.

Not to be used for diagnostic or therapeutic applications.