FOX04-DRI 10mg

FOXO4-DRI Peptide 10mg – Research-Grade Senolytic Peptide (≥99% Purity)

FOXO4-DRI (Forkhead box O4–D-Retro-Inverso peptide) is a synthetic peptide analog developed to selectively modulate the interaction between FOXO4 and p53, a pathway associated with cellular senescence. This peptide has been widely studied in senescence-focused models, especially in age-related and degenerative condition research.

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Peptide Specifications

• Peptide Type: D-Retro-Inverso analog of FOXO4
• Sequence: Custom-engineered based on FOXO4-p53 interaction domain
• Purity: ≥99% (HPLC Verified)
• Appearance: White, lyophilised powder
• Solubility: DMSO or laboratory-grade water
• Storage: 2–8°C (short term), –20°C (long term)
• Packaging: Sterile 10mg glass vial, free of excipients such as mannitol

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Research Highlights

• Senolytic Exploration: FOXO4-DRI has been used in preclinical studies to explore the clearance of senescent cells via disruption of FOXO4-p53 binding.
• Cellular Aging Models: Commonly applied in research involving age-associated decline, organ dysfunction, and cell cycle arrest.
• Mechanism-Focused Studies: Enables targeted analysis of apoptotic pathways in senescent cell populations, making it valuable for anti-aging and regeneration-based research.
• Referential Study: Groundbreaking work by Baar et al. (Cell, 2017) showcased FOXO4-DRI’s effects in murine models, sparking widespread interest in senescence-targeted studies.

🧪 No Fillers. No Additives.

This peptide is supplied as a pure research compound, free from mannitol or sugar-based binders, ensuring clarity and reliability in laboratory reconstitution and experimental control.

🔒 For Research Use Only

Not intended for human consumption or therapeutic application.

To be used exclusively in laboratory, in vitro, or scientific research settings.